renin-angiotensin-aldosterone system

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• Renin-angiotensin system — The renin angiotensin system (RAS) or the renin angiotensin aldosterone system (RAAS) is a hormone system that regulates blood pressure and water (fluid) balance. When blood pressure is low, the kidneys secrete renin. Renin stimulates the… …   Wikipedia

• renin-angiotensin system — (RAS), renin angiotensin aldosterone system (RAAS) the regulation of sodium balance, fluid volume, and blood pressure by renal secretions: in response to reduced perfusion, renin is secreted, which hydrolyzes a plasma globulin to release… …   Medical dictionary

• Angiotensin — causes blood vessels to constrict, and drives blood pressure up. It is part of the renin angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also creates aldosterone, which causes the tubules of the… …   Wikipedia

• Angiotensin II receptor type 1 — Angiotensin II receptor, type 1 or AT1 receptor is an angiotensin receptor. It has vasopressor effects and regulates aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system.It is the… …   Wikipedia

• Angiotensin II receptor antagonist — Angiotensin II receptor antagonists, also known as angiotensin receptor blockers (ARBs), AT1 receptor antagonists or sartans, are a group of pharmaceuticals which modulate the renin angiotensin aldosterone system. Their main use is in… …   Wikipedia

• Aldosterone synthase — (or 18 hydroxylase) is a steroid hydroxylase cytochrome P450 oxidase enzyme involved in the generation of aldosterone. PBB Summary section title = summary text = This gene encodes a member of the cytochrome P450 superfamily of enzymes. The… …   Wikipedia

• renin-aldosterone axis — renin angiotensin axis renin angiotensin aldosterone system …   Medical dictionary

• renin-angiotensin system — ▪ physiology       physiological system that regulates blood pressure.        renin is an enzyme secreted into the blood from specialized cells (cell) that encircle the arterioles at the entrance to the glomeruli of the kidneys (kidney) (the… …   Universalium

• renin — A term originally used for a pressor substance obtained from rabbits kidneys, now an enzyme that converts angiotensinogen to angiotensin I. SYN: angiotensinogenase. * * * re·nin rē nənalso ren ən n a proteolytic enzyme of the blood that is… …   Medical dictionary

• Discovery and development of renin inhibitors — Renin inhibitors are antihypertensive drugs that inhibit the first and rate limiting step of the renin angiotensin aldosterone system (RAAS). Since the 1970s scientists have been trying to develop potent inhibitors with acceptable oral… …   Wikipedia

• Renin — Protbox Name=Renin Photo=Renin.png Caption=Molecular structure of renin HGNCid = 9958 Symbol = REN AltSymbols = Names=Angiotensinogenase Chromosome = 1 Arm = q Band = 32 LocusSupplementaryData = Gene= Gene type= Protein length=406 Molecular… …   Wikipedia